The Ohlone College Science and Math Seminar Series program features distinguished speakers who address interesting topics related to science, mathematics, or technology.
Sponsored by ASOC and Ohlone's Science, Engineering, and Mathematics Division. The seminars are free and open to the public.
Please check back for additional Science Seminars.
- Battling Breast Cancer with Broccoli: Estrogen Signaling modulation by Indole-3-Carbinol
by Professor Shyam Sundar, Biology Department
- Friday, March 6, 2015, 12:00pm - 1:00pm
- Room 3101, Building 3, first floor, Fremont campus
- Estrogen signaling is a critical component of breast cell and breast cancer biology. Estrogen signaling has been positively implicated in the development of breast cancer. Estrogens have been known to bind and activate two subtypes of receptors: estrogen receptor alpha and estrogen receptor beta. These receptors have antagonistic effects on breast cell mitosis. Indole-3-Carbinol is an anticancer chemical derived from broccoli that has been shown to inhibit growth of breast cancer cells in culture as well as in animal models. This presentation brings to light the effects of indole-3-carbinol on estrogen receptor signaling in human breast cancer cells.